Sono-Photo Dynamic Therapy (SPDT)

Targeted Cancer Therapy Using Sound and Light

Sono-Photo Dynamic Therapy


Hope4Cancer is the pioneering treatment center in the world for one of our signature anticancer therapies: Sono-Photo Dynamic Therapy (SPDT). This therapy uses non-toxic sensitizers that selectively concentrate in cancer cells, and can be activated using predetermined sound (Sono-Dynamic Therapy) and light (Photo-Dynamic Therapy) frequencies. Introduced in 2004 (and with more than 2000 patients treated), Sono-Photo Dynamic Therapy has stood the test of time as a safe, non-toxic treatment approach for a variety of cancers.


As part of our commitment to stay on the leading edge, Hope4Cancer is now proud to feature Low Level Laser Light Therapy (also known as Photobiomodulation) that uses the world’s most advanced laser technology for a variety of metabolic benefits. However, using different, specific wavelengths, these lasers also activate a variety of sensitizers (Photodynamic Therapy Plus). The use of this technology dramatically increases our ability to impact a wide range of cancers that may or may not respond to any individual sensitizer. The laser light is delivered both intravenously and interstitially through minimally invasive procedures.

In addition to laser-based therapies, our treatments also use light beds that provide full spectrum light to treat the entire body, affecting both local malignancies and areas of metastasis. Advanced pulsed LED light technology delivers LED light at greater depths of penetration than other available light sources.

Sono-Dynamic Therapy is accomplished using ultrasound technology, capable of delivering the appropriate sound frequency to activate the absorbed sensitizer. Sound can easily penetrate through human tissue, making Sono-Dynamic Therapy highly effective in treating deep-seated tumors.

Once activated, the sensitizer agent reacts with oxygen to release energy in the form of reactive oxygen species (ROS), effectively killing the cancer cells. Simultaneously, this release also damages the vascular network (which feeds nutrients to tumor cells) while rapidly recruiting immune cells to the cancer site, favoring the development of adaptive immunity. One of the common observations in our cancer patients is a drastic reduction in blood flow into the tumor, reducing the nutrition available for the sustenance of the surviving cancer cells.

Because of the sensitizer’s universal affinity to malignant cells, Sono-Photo Dynamic Therapy has been used to treat a variety cancers. These include but are not limited to breast cancer, colorectal cancer, prostate cancer, liver cancer, ovarian cancer, brain cancer, lung cancer, cervical cancer, melanoma, bone cancer, esophageal cancer, stomach cancer, pancreatic cancer, head and neck cancers, bladder cancer, thyroid cancer, uterine cancer, vaginal cancer, lymphoma, sarcomas, and leukemia.

Originally developed in the 1800s, Photo Dynamic Therapy was limited by the toxicity of agents and the weak penetration of available light sources. However, recent discoveries have allowed this treatment method to take advantage of non-toxic sensitizers that are also activated by sound.

(Disclaimer: Hope4Cancer treats cancer patients with Sono-Photo Dynamic Therapy, Photobiomodulation or Low Level Laser Light Therapy, and Photodynamic Therapy Plus only at its Mexico treatment centers; we do not make these treatments available outside the borders of Mexico under any circumstances. Hope4Cancer Treatment Centers make no claim that these therapies are a cure for cancer. Each patients situation is different and results vary.).


  1. Macdonald, I. J., & Dougherty, T. J. (2001). Basic principles of photodynamic
    therapy. Journal of Porphyrins and Phthalocyanines, 5, 105-129.
  2. Dolmans, D. E., Fukumura, D., & Jain, R. K. (2003). Photodynamic therapy for
    cancer. Nature Reviews Cancer, 3(5), 380.
  3. Castano, A. P., Mroz, P., & Hamblin, M. R. (2006). Photodynamic therapy and anti-tumour immunity. Nature Reviews Cancer, 6(7), 535.
  4. Abdel-Kader, M. H. (Ed.). (2014). Photodynamic Therapy: From Theory to Application. Springer Science & Business Media.
  5. Hamblin, M. R., & Huang, Y. (Eds.). (2013). Handbook of Photomedicine. Taylor & Francis.
Dr Tony High Fives A Patient

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